BDBM50566354 CHEMBL4853103

SMILES CCCOc1nncc(n1)-c1cnnc(OCCN(C)C)n1

InChI Key InChIKey=LPUWNMUGLGACON-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50566354   

TargetCytochrome P450 3A4(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50566354(CHEMBL4853103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in testosterone 6beta-hydroxylation activity by high-pressure liquid chromatogra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50566354(CHEMBL4853103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50566354(CHEMBL4853103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50566354(CHEMBL4853103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50566354(CHEMBL4853103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50566354(CHEMBL4853103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed