BDBM50566516 CHEMBL4856594

SMILES C[C@H]1COc2c3c(cc(c2N4CC[C@H](C4)C5(CC5)N)F)C=C(C(=O)N31)C(=O)O

InChI Key InChIKey=KUJKUYSIFHKKCZ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50566516   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50566516(CHEMBL4856594)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50566516(CHEMBL4856594)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50566516(CHEMBL4856594)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human Cav1.2 expressed in CHO-K1 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed