BDBM50566516 CHEMBL4856594

SMILES C[C@H]1COc2c(N3CC[C@H](C3)C3(N)CC3)c(F)cc3cc(C(O)=O)c(=O)n1c23

InChI Key InChIKey=KUJKUYSIFHKKCZ-CMPLNLGQSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50566516   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50566516(CHEMBL4856594)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50566516(CHEMBL4856594)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human Cav1.2 expressed in CHO-K1 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50566516(CHEMBL4856594)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed