BDBM50567341 CHEMBL4871087

SMILES ONC(=O)c1cccc(c1)C(=O)NOCc1ccc(Cl)cc1Cl

InChI Key InChIKey=AKSVFMBZKMKUPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567341   

TargetHistone deacetylase 8(Blood fluke)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567341(CHEMBL4871087)
Affinity DataIC50: 400nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567341(CHEMBL4871087)
Affinity DataIC50: 630nMAssay Description:Inhibition of human HDAC8 using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567341(CHEMBL4871087)
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of human HDAC6 using Z-Lys(Ac)-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed