BDBM50567460 CHEMBL4868257

SMILES CC(C)(C)c1ccc(cc1)-c1ncc(OCC2CCNCC2)nc1-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=YEVZILDZTUEBRX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50567460   

TargetNonstructural protein 3(ZIKV)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567460(CHEMBL4868257)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition Zika virus NS3B (47 to 95 residues)/NS3 (1 to 170 residues) protease expressed in Escherichia coli BL21 using 7-amino-4-methylcoumarin as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567460(CHEMBL4868257)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567460(CHEMBL4868257)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition West Nile virus NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567460(CHEMBL4868257)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed