BDBM50567476 CHEMBL4858157

SMILES C(Oc1cnc(-c2ccc(cc2)-c2ccoc2)c(n1)-c1ccc(cc1)-c1ccoc1)C1CCNCC1

InChI Key InChIKey=QLCHGDXZIUOABP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50567476   

TargetNonstructural protein 3(ZIKV)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition Zika virus NS3B (47 to 95 residues)/NS3 (1 to 170 residues) protease expressed in Escherichia coli BL21 using 7-amino-4-methylcoumarin as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human p300 HAT domain (1195 to 1673 residues) using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCREB-binding protein(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human CBP-HAT domain using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of biotinylated histone H4 peptide binding to His-tagged human p300 HAT domain (1195 to 1673 residues) assessed as reduction in alpha sign...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Myst3 using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50567476(CHEMBL4858157)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PCAF using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed