BDBM50568248 CHEMBL4879105

SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)C1

InChI Key InChIKey=LGDCOYCPANTWSM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50568248   

TargetHistone deacetylase 7(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50568248(CHEMBL4879105)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-4-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50568248(CHEMBL4879105)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human recombinant HDAC4 (627 to 1084 residues) expressed in baculovirus-infected Sf9 cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50568248(CHEMBL4879105)
Affinity DataIC50: 48nMAssay Description:Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50568248(CHEMBL4879105)
Affinity DataIC50: 61nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant full length HDAC5 expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50568248(CHEMBL4879105)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant full length HDAC3 (1 to 428 residues)/N-terminal GST-tagged human recombinant NCOR2 (395 to 489...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed