BDBM50568771 CHEMBL4846201

SMILES CC(CCCc1ccccc1)CNC(=O)\N=C(/N)NCCCc1sc(N)nc1C

InChI Key InChIKey=TYUKINNXLNULMD-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50568771   

TargetD(3) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataEC50:  417nMAssay Description:Agonist activity at human histamine D3 receptor receptor expressed in HEK293T cells co-expressing ELucC by beta arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataKi:  589nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataKi:  776nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataKi:  2.29E+3nMAssay Description:Displacement of [3H]UR-P129 from human histamine H3 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at human histamine H2 receptor expressed in HEK293T cells co-expressing ELucC by beta arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataEC50:  2.95E+3nMAssay Description:Agonist activity at human histamine D2L receptor receptor expressed in HEK293T cells co-expressing ELucC by beta arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568771BDBM50568771(CHEMBL4846201)
Affinity DataKi:  7.08E+3nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in sf9 insect cell membranes co-expressing RGS4 incubated for 60 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed