BDBM50568779 CHEMBL4878215

SMILES N\C(NC1CCc2nc(N)sc2C1)=N/C(=O)NCc1ccccc1

InChI Key InChIKey=KOIIIBWVKNCMBP-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50568779   

TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataEC50:  214nMAssay Description:Agonist activity at human histamine receptor expressed in sf9 insect cell membranes co-exprssing GsalphaS incubated for 90 mins [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataKi:  513nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataKi:  550nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in sf9 insect cell membranes co-expressing RGS4 incubated for 60 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataKi:  3.31E+3nMAssay Description:Displacement of [3H]UR-P129 from human histamine H3 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataEC50:  4.37E+3nMAssay Description:Agonist activity at human histamine H2 receptor expressed in HEK293T cells co-expressing ELucC by beta arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568779BDBM50568779(CHEMBL4878215)
Affinity DataKi:  3.02E+4nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed