BDBM50568784 CHEMBL4872375

SMILES CCCCCCNC(=O)\N=C(/N)Nc1cccc(c1)-c1csc(N)n1

InChI Key InChIKey=LMIAIPKXPWLPGV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50568784   

TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568784BDBM50568784(CHEMBL4872375)
Affinity DataKi:  692nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568784BDBM50568784(CHEMBL4872375)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568784BDBM50568784(CHEMBL4872375)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568784BDBM50568784(CHEMBL4872375)
Affinity DataKi:  9.55E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568784BDBM50568784(CHEMBL4872375)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [3H]UR-P129 from human histamine H3 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed