BDBM50568939 CHEMBL4849134
SMILES CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c3n2)cc1
InChI Key InChIKey=LATMRUSMLRSPOU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50568939
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston
Curated by ChEMBL
University Of Houston
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair