BDBM50569927 CHEMBL4851961
SMILES COc1cccc(CCn2c3-c4ccccc4C(=O)c3c3c(OCCCCOc4cccc5n(CCc6cccc(OC)c6)c6-c7ccccc7C(=O)c6c45)cccc23)c1
InChI Key InChIKey=CRWOJYZPWVKILL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50569927
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Uncompetitive inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki2 for inhibition of mitoxantrone efflux measured after 30 min...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Mixed inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki2 for inhibition of Hoechst33342 efflux measured after 30 mins by FAC...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataKi: 113nMAssay Description:Mixed inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki1 for inhibition of Hoechst33342 efflux measured after 30 mins by FAC...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human ABCG2 transfected in human HEK293 cells assessed as inhibition of mitoxantrone efflux measured after 30 mins by FACS Calibur cyto...More data for this Ligand-Target Pair