BDBM50570512 CHEMBL4858425::US11753371, Compound II-2e

SMILES CCN(CCO)C(=S)SSC(=S)N(CC)CCO

InChI Key InChIKey=OQYXONFXDGOXHY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50570512   

TargetMonoglyceride lipase(Human)
Batterjee Medical College

US Patent
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 720nMAssay Description:The compounds II-2a to II-2m and controls in Table II were tested in 10-dose IC50 mode, with 3-fold serial dilution at a starting concentration of 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Batterjee Medical College

US Patent
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 720nMAssay Description:The compounds II-2a to II-2m and controls in Table II were tested in 10-dose IC50 mode, with 3-fold serial dilution at a starting concentration of 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent

TargetAldehyde dehydrogenase 1A1(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of ALDH1A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAldehyde dehydrogenase 1A1(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.54E+3nMAssay Description:ALDH Assay Protocols: 5 μl of enzyme (150 nM for ALDH1a1 and 200 nM for ALDH2 in reaction buffer) were delivered to assay wells in corning black, 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetAldehyde dehydrogenase 1A1(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.54E+3nMAssay Description:5 μl of enzyme (150 nM for ALDH1a1 and 200 nM for ALDH2 in reaction buffer) were delivered to assay wells in coming black, 384 well plate. 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Batterjee Medical College

US Patent
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.54E+4nMAssay Description:FAAH inhibition assay was performed using Fatty Acid Amide Hydrolase Inhibitor Screening Assay Kit (Item #10005196), Cayman (1180 E Ellsworth Rd Ann ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Batterjee Medical College

US Patent
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.54E+4nMAssay Description:FAAH inhibition assay was performed using Fatty Acid Amide Hydrolase Inhibitor Screening Assay Kit (Item #10005196), Cayman (1180 E Ellsworth Rd Ann ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of ALDH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAldehyde dehydrogenase, mitochondrial(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.57E+4nMAssay Description:5 μl of enzyme (150 nM for ALDH1a1 and 200 nM for ALDH2 in reaction buffer) were delivered to assay wells in coming black, 384 well plate. 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50570512(CHEMBL4858425 | US11753371, Compound II-2e | US202...)
Affinity DataIC50: 2.57E+4nMAssay Description:ALDH Assay Protocols: 5 μl of enzyme (150 nM for ALDH1a1 and 200 nM for ALDH2 in reaction buffer) were delivered to assay wells in corning black, 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent