BDBM50570845 CHEMBL4877613

SMILES Cc1ccc(CN2CCCC2C(=O)Nc2ccccc2Oc2cccnc2)cc1

InChI Key InChIKey=CYCZYDSXTWKZGE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570845   

TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570845(CHEMBL4877613)
Affinity DataEC50:  530nMAssay Description:Activation of N-terminal His-tagged human NAMPT expressed in Escherichia coli BL 21 (DE3) using NAM and PRPP as substrates incubated for 15 mins in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50570845(CHEMBL4877613)
Affinity DataEC50:  530nMAssay Description:Activation of human NAMPT assessed as increase in NMN production by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed