BDBM50570943 CHEMBL4870495

SMILES CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2ccccc2)cc1C

InChI Key InChIKey=FYRWUAWBPDXQPZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570943   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
Hibercell

Curated by ChEMBL

LigandBDBM50570943(CHEMBL4870495)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy BDB DOIPubMed
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TargetEukaryotic translation initiation factor 2 subunit 1(Human)
Hibercell

Curated by ChEMBL

LigandBDBM50570943(CHEMBL4870495)Copy SMILESCopy InChI

Affinity DataIC50: 198nMAssay Description:Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL