BDBM50570994 CHEMBL4863999

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=XNOMSXYPJLBWKR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50570994   

TargetCarbonic anhydrase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570994(CHEMBL4863999)
Affinity DataKi:  0.00900nMAssay Description:Inhibition of human CA2 using 4-nitrophenylacetate as substrate incubated for 10 mins prior to testing by spectrophotometry based esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570994(CHEMBL4863999)
Affinity DataIC50: 210nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570994(CHEMBL4863999)
Affinity DataIC50: 650nMAssay Description:Inhibition of human CA9 using 4-nitrophenylacetate as substrate incubated for 10 mins prior to testing by spectrophotometry based esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570994(CHEMBL4863999)
Affinity DataIC50: 950nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570994(CHEMBL4863999)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CA1 using 4-nitrophenylacetate as substrate incubated for 10 mins prior to testing by spectrophotometry based esterase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570994(CHEMBL4863999)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed