BDBM50571949 CHEMBL4874534

SMILES CN1CCC(CN2CCc3c(C2)ncnc3Oc2ccc(NC(=O)c3cn(CCF)c(=O)n(-c4ccc(F)cc4)c3=O)cc2F)CC1

InChI Key InChIKey=OSQTZXWCOXMSCA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571949   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50571949(CHEMBL4874534)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of Axl (unknown origin) by cell free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571949(CHEMBL4874534)
Affinity DataIC50:  130nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571949(CHEMBL4874534)
Affinity DataIC50:  49nMAssay Description:Inhibition of Axl in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50571949(CHEMBL4874534)
Affinity DataIC50:  150nMAssay Description:Inhibition of Mer (unknown origin) by cell free assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed