BDBM50573069 CHEMBL4857008

SMILES Cc1c(c(C(=O)CC2CC2)n(C)c1-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=MUCQIHPPMKTGJF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573069   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50573069(CHEMBL4857008)
Affinity DataEC50:  1.04E+3nMAssay Description:Type-II positive allosteric modulation of alpha7 nAChR in human IMR-32 cells assessed as increase in choline chloride-induced Ca2+ flux preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50573069(CHEMBL4857008)
Affinity DataEC50:  1.04E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR in human IMR-32 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed