BDBM50573139 CHEMBL4856195

SMILES CN(Cc1ccc2nccn2c1)c1nnc(o1)-c1ccc(cc1C)-c1c(C)nc(C)n1C

InChI Key InChIKey=ZNGCWFPZUBLLOJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50573139   

TargetTyrosine-protein kinase Mer(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573139(CHEMBL4856195)
Affinity DataIC50: 40nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573139(CHEMBL4856195)
Affinity DataIC50: 501nMAssay Description:Inhibition of FLAG-tagged MER (unknown origin) transfected in Cos-7cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573139(CHEMBL4856195)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of AXL (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573139(CHEMBL4856195)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of FLAG-tagged AXL (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573139(CHEMBL4856195)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of FLT3 (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573139(CHEMBL4856195)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of FLAG-tagged FLT3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed