BDBM50573321 CHEMBL4280104

SMILES [N-]=[N+]=NCCOCCOCCOc1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=VAHYXNIJBAGFQO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50573321   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Hong Kong Polytechnic University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573321BDBM50573321(CHEMBL4280104)
Affinity DataEC50:  363nMAssay Description:Inhibition of BCRP (unknown origin) transfected in HEK293/R2 cells assessed as reversal of topotecan resistance after 5 days by MTS/PMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed