BDBM50573453 CHEMBL4858472

SMILES CNC(=O)N1N=C(c2ccc(cc2)N2CCN(CC2)C(=O)COCCOCCOCC(=O)Nc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)c2cc(OC)c(OC)cc2C[C@@H]1C

InChI Key InChIKey=GPLNUDIJFMSVJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573453   

TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573453(CHEMBL4858472)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human His-tagged BRD4 BD1 using biotin-labelled histone H4 acetylated peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573453(CHEMBL4858472)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human His-tagged BRD4 BD2 using biotin-labelled histone H4 acetylated peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed