BDBM50573713 CHEMBL4859304::US12565495, Example 19

SMILES COc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC1CC1

InChI Key InChIKey=HSVRNWDLNHQKIR-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50573713   

TargetSynaptic vesicular amine transporter(Rat)
Luye Innomind Pharma Shijiazhuang Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50573713BDBM50573713(CHEMBL4859304 | US12565495, Example 19)
Affinity DataKi:  1.34nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2026
Entry Details
US Patent

TargetSynaptic vesicular amine transporter(Rat)
Luye Innomind Pharma Shijiazhuang Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50573713BDBM50573713(CHEMBL4859304 | US12565495, Example 19)
Affinity DataIC50: 2.30nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2026
Entry Details
US Patent

TargetSynaptic vesicular amine transporter(Rat)
Luye Innomind Pharma Shijiazhuang Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50573713BDBM50573713(CHEMBL4859304 | US12565495, Example 19)
Affinity DataIC50: 5.99nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2026
Entry Details
US Patent

TargetSynaptic vesicular amine transporter(Rat)
Luye Innomind Pharma Shijiazhuang Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50573713BDBM50573713(CHEMBL4859304 | US12565495, Example 19)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Luye Innomind Pharma Shijiazhuang Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50573713BDBM50573713(CHEMBL4859304 | US12565495, Example 19)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed