BDBM50573714 CHEMBL4867332::US12565495, Example 17

SMILES COCCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC

InChI Key InChIKey=UZMMDWDRHARBKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50573714   

TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573714BDBM50573714(CHEMBL4867332 | US12565495, Example 17)
Affinity DataIC50: 58nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573714BDBM50573714(CHEMBL4867332 | US12565495, Example 17)
Affinity DataIC50: 58nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2026
Entry Details
US Patent

TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50573714BDBM50573714(CHEMBL4867332 | US12565495, Example 17)
Affinity DataIC50: 65nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed