BDBM50573819 CHEMBL4879107

SMILES Nc1ccc(cc1)-c1ccc(Nc2ncc(Cl)c(Nc3cccc(c3)C(F)(F)F)n2)nc1

InChI Key InChIKey=ACTYGNXJGLFMRG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573819   

TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50573819BDBM50573819(CHEMBL4879107 | US12595236, Compound 59)
Affinity DataIC50: 158nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50573819BDBM50573819(CHEMBL4879107 | US12595236, Compound 59)
Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition incubated for 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50573819BDBM50573819(CHEMBL4879107 | US12595236, Compound 59)
Affinity DataIC50: 251nMAssay Description:Inhibition of human Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50573819BDBM50573819(CHEMBL4879107 | US12595236, Compound 59)
Affinity DataIC50: 281nMAssay Description:Inhibition of human Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed