BDBM50574277 CHEMBL4871106
SMILES NC(=O)c1cccc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12
InChI Key InChIKey=HXAUJHZZPCBFPN-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50574277
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...More data for this Ligand-Target Pair