BDBM50575299 CHEMBL4874749

SMILES CC(=O)N1CCC(c2cnc(NCc3c(F)ccc4c3CCO4)c3cn[nH]c(=O)c23)CC1

InChI Key InChIKey=XUMXPJUJQTVJDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575299   

TargetPolycomb protein EED(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575299BDBM50575299(CHEMBL4874749)
Affinity DataIC50: 75nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575299BDBM50575299(CHEMBL4874749)
Affinity DataIC50: 79nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed