BDBM50575490 CHEMBL4874303

SMILES COc1cnc(Oc2ccc(cc2)-c2nnn(C[C@H](N)CC(O)=O)n2)nc1

InChI Key InChIKey=ZBZMVFMJBAUXKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575490   

TargetLeukotriene A-4 hydrolase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50575490(CHEMBL4874303)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50575490(CHEMBL4874303)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed