BDBM50575916 CHEMBL4879253

SMILES COc1cccc2nn[nH]c12

InChI Key InChIKey=BFBZLCUTOUZMLJ-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575916   

TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50575916(CHEMBL4879253)
Affinity DataKd:  1.40E+6nMAssay Description:Binding affinity to human recombinant His-tagged Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissoc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50575916(CHEMBL4879253)
Affinity DataKi:  3.10E+6nMAssay Description:Inhibition of interaction between human KEAP1 Kelch domain/FAM-Nrf2 using Cy5-Nrf2 incubated for 10 to 15 mins by competitive fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed