BDBM50576735 CHEMBL4868627

SMILES FC(F)(F)CCn1cc(cn1)-c1c(nc2ccc(Cl)cn2c1=O)C(F)(F)F

InChI Key InChIKey=ZDMPWZHAMMRBMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576735   

TargetAcyl-CoA (8-3)-desaturase(Human)
AMGEN INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 50576735BDBM50576735(CHEMBL4868627 | US12473289, Example 39-17)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetAcyl-CoA (8-3)-desaturase(Human)
AMGEN INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 50576735BDBM50576735(CHEMBL4868627 | US12473289, Example 39-17)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed