BDBM50576736 CHEMBL4872983

SMILES Cc1ccc2nc(c(-c3cnn(CC(F)(F)C(F)(F)F)c3)c(=O)n2c1)C(F)(F)F

InChI Key InChIKey=PZAMUSYHUVFPMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576736   

TargetAcyl-CoA (8-3)-desaturase(Human)
AMGEN INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 50576736BDBM50576736(CHEMBL4872983 | US12473289, Example 39-19)
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details US Patent

TargetAcyl-CoA (8-3)-desaturase(Human)
AMGEN INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 50576736BDBM50576736(CHEMBL4872983 | US12473289, Example 39-19)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed