BDBM50576737 CHEMBL4855704::US12473289, Example 39-23

SMILES Fc1ccc2nc(c(-c3cnn(CC(F)(F)C(F)(F)F)c3)c(=O)n2c1)C(F)(F)F

InChI Key InChIKey=GKLIIBNZHOFAMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576737   

TargetAcyl-CoA (8-3)-desaturase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576737BDBM50576737(CHEMBL4855704 | US12473289, Example 39-23)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Delta-5-desaturase (unknown origin) expressed in HEK2936E cell membrane incubated for 1 hr by DGLA-CoA and Arachidonyl-CoA mass spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576737BDBM50576737(CHEMBL4855704 | US12473289, Example 39-23)
Affinity DataIC50: 2.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details