BDBM50576765 CHEMBL4863830

SMILES OC[C@@H](O[C@H]1CCCN(Cc2c[nH]c3cc(ccc23)C(O)=O)[C@H]1c1ccccc1)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=KTWOGEHBLBGZDY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576765   

TargetcGMP-dependent protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50576765(CHEMBL4863830)
Affinity DataEC50:  2.20E+4nMAssay Description:Activation of full length PKG1alpha (unknown origin) using Glass-tide peptide substrate incubated for 120 mins followed by addition of ADP-Glo max re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50576765(CHEMBL4863830)
Affinity DataEC50:  1.40E+5nMAssay Description:Activation of PKG1alpha (unknown origin) in human HEK293 cellls assessed as VSAP phosphorylation at Ser 239 incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed