BDBM50577406 CHEMBL4862806

SMILES Cc1ccc(cc1C#Cc1cc(cnc1N)-c1cnn(C)c1)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=CEUSZLVORFRBCV-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50577406   

TargetTyrosine-protein kinase HCK(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant HCK (230 to 497) by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 9nMAssay Description:Inhibition of human full length recombinant LYN by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant Src (1-530) by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant ABL1 using ATP/Ulight-TK peptide incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant FGR (456 to 770) radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide at 50 nM incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide incubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 56nMAssay Description:Inhibition of human full length recombinant Fyn by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 56nMAssay Description:Inhibition of human full length recombinant BLK by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 95nMAssay Description:Inhibition of human full length recombinant Yes by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 101nMAssay Description:Inhibition of human full length recombinant LCK by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Srms(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 114nMAssay Description:Inhibition of human SRMS by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 126nMAssay Description:Inhibition of human full length recombinant Bmx by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 185nMAssay Description:Inhibition of human recombinant Txk (256 to end) by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50577406(CHEMBL4862806)
Affinity DataIC50: 187nMAssay Description:Inhibition of human full length recombinant CSK by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed