BDBM50578093 CHEMBL4848146

SMILES Nc1ccc(Br)c2ccncc12

InChI Key InChIKey=BTFXYVXBWMRHIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578093   

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM50578093(CHEMBL4848146 | US12338238, Example 12)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2025
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50578093(CHEMBL4848146 | US12338238, Example 12)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of Axl (unknown origin) using 5'FAM labeled KKKKEEIYFFF-NH2 peptide as substrate incubated for 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed