BDBM50580044 CHEMBL5085639

SMILES CC[C@@H](CC(F)(F)F)n1cnnc1-c1cccc(n1)N1Cc2c(cc(OC)cc2CNC)C1=O

InChI Key InChIKey=JSGLVFKXVZJWDM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50580044   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580044(CHEMBL5085639)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed