BDBM50580082 CHEMBL5079215
SMILES CN(C(=O)Nc1cc(NC(=O)NCCC(C)(C)C)c(F)cc1C)c1cc(N)ncn1
InChI Key InChIKey=MKBZBPSOGSNHLZ-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50580082
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: <0.0500nMAssay Description:Inhibition of CRAF Y340D/Y341D mutant (unknown origin) using inactive MAP2K1 as substrate preincubated for 30 mins measured after 90 mins by DELFIA a...More data for this Ligand-Target Pair
Affinity DataKi: <0.0800nMAssay Description:Inhibition of BRAF (unknown origin) (416 to 766) inactive MAP2K1 as substrate preincubated for 30 mins measured after 90 mins by DELFIA assayMore data for this Ligand-Target Pair