BDBM50580098 CHEMBL5075948

SMILES Cc1cn([C@H]2C[C@@H](n3cc(COC(=O)c4ccc(S(N)(=O)=O)cc4)nn3)[C@@H](CO)O2)c(=O)[nH]c1=O

InChI Key InChIKey=QUZPAHPBEBDURD-UHFFFAOYSA-N

Data  7 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50580098   

TargetCarbonic anhydrase 2(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  7nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  28nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  49nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  54nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of telomerase in human HCT-116 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of telomerase in human COLO 205 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of telomerase in human SW-620 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580098BDBM50580098(CHEMBL5075948)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of telomerase in human HT-29 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed