BDBM50580522 CHEMBL5082650

SMILES Nc1nc2-c3cc(OCCCN4CCCCC4)ccc3C(=O)c2c(n1)-c1ccccc1

InChI Key InChIKey=FDGXVDUYFWJNRM-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50580522   

TargetAdenosine receptor A2a(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  52nMAssay Description:Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  364nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D3 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]SCH23390 from human recombinant dopamine D5 receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2S receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580522(CHEMBL5082650)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in sf9 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed