BDBM50580605 CHEMBL5088737

SMILES COc1cc(OC)cc(c1)-c1nn(CCCCCN2CCN(CC2)C(=O)\C=C\C(F)(F)F)c2ncnc(N)c12

InChI Key InChIKey=YISJWEXLNFHRNW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50580605   

TargetFibroblast growth factor receptor 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580605(CHEMBL5088737)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human FGFR2 (458 to 768 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580605(CHEMBL5088737)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human FGFR1 (459 to 765 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580605(CHEMBL5088737)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human FGFR3 (450 to 758 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580605(CHEMBL5088737)
Affinity DataIC50: 809nMAssay Description:Inhibition of human FGFR4 (445 to 753 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580605(CHEMBL5088737)
Affinity DataIC50: 3.21E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed