BDBM50581351 CHEMBL5086378

SMILES OC(=O)CCc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O

InChI Key InChIKey=ALLMKXCUURSYGS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581351   

LigandPNGBDBM50581351(CHEMBL5086378)
Affinity DataKi:  490nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from MCL1 (unknown origin) incubated for 2 hrs by fluorescence polarization-based competitive bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581351(CHEMBL5086378)
Affinity DataKi:  2.38E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from Bcl-2 (unknown origin) incubated for 2 hrs by fluorescence polarization-based competitive bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50581351(CHEMBL5086378)
Affinity DataKi:  3.30E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from Bcl-xl (unknown origin) incubated for 2 hrs by fluorescence polarization-based competitive b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed