BDBM50581678 CHEMBL5072502

SMILES COc1ccc2[nH]cc(CCN(Cc3ccc(cc3)C(=O)NO)C(=O)\C=C\c3ccc(O)c(OC)c3)c2c1

InChI Key InChIKey=BOSHROJUQKKPJB-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50581678   

TargetHistone deacetylase 9(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 771nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(Ac)-AMC as substrate pre-incubated for 1 hr followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 776nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(Ac)-AMC as substrate pre-incubated for 1 hr followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Boc-Lys(Ac)-AMC as substrate pre-incubated for 1 hr followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Boc-Lys(Ac)-AMC as substrate pre-incubated for 1 hr followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed