BDBM50581853 CHEMBL5083308

SMILES Cc1nc(C(=O)NCC(C)(O)C(F)(F)F)c(N)cc1C(F)(F)F

InChI Key InChIKey=YHKUZELTNIAEGX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50581853   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50581853(CHEMBL5083308)
Affinity DataEC50:  240nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in CHO cells assessed as chloride transport by measuring membrane potential incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed