BDBM50582272 CHEMBL5084123

SMILES [H][C@@]12C[C@@]([H])(C=C1)[C@@H]([C@@H]2Nc1nc(Nc2cc(F)cc(c2)N2CCOCC2)ncc1-c1cccc(F)c1)C(N)=O

InChI Key InChIKey=SFXNZFNSPSLHEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582272   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50582272(CHEMBL5084123)
Affinity DataIC50: 12nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of MBP as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50582272(CHEMBL5084123)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TAK1 (unknown origin) in presence of MBP as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed