BDBM50582598 CHEMBL5074880

SMILES CCNCc1ccc(Cl)c(c1)-c1ccccc1OC

InChI Key InChIKey=MNZKMXOYJBDBSR-UHFFFAOYSA-N

Data  12 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50582598   

Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H] D-lysergic acid diethylamide from 5-HT7R (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by microbeta scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  10nMAssay Description:Displacement of [3H] D-lysergic acid diethylamide from 5-HT7R (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by microbeta scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  19nMAssay Description:Binding affinity to 5-HT2BR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  45nMAssay Description:Binding affinity to 5-HT2CR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  210nMAssay Description:Binding affinity to 5-HT1BR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  220nMAssay Description:Binding affinity to 5-HT1DR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataEC50:  759nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataEC50:  770nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  840nMAssay Description:Binding affinity to 5-HT1AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  910nMAssay Description:Binding affinity to 5-HT2AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to 5-HT6R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to 5-HT5AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT1ER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582598(CHEMBL5074880)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT3R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed