BDBM50582618 CHEMBL5091929

SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CN(C(=O)C2)C2=CC(=O)OC2)CC1

InChI Key InChIKey=WJLWVTZSDBXNKW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582618   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50582618(CHEMBL5091929)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50582618(CHEMBL5091929)Copy SMILESCopy InChI

Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK-293 cells by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL