BDBM50582619 CHEMBL5084415

SMILES Cc1c([C@@H](O)CN2CCC3(CC2)CCN(C2=CC(=O)OC2C)C3=O)ccc2c1COC2=O

InChI Key InChIKey=YTPYVSHGPFPSMP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582619   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50582619(CHEMBL5084415)Copy SMILESCopy InChI

Affinity DataIC50: 24nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50582619(CHEMBL5084415)Copy SMILESCopy InChI

Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human ERG expressed in HEK-293 cells by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL