BDBM50582924 CHEMBL5084107

SMILES COc1ccc(OC)c(c1)-c1nc(SCC(=O)c2ccc(Br)cc2)nc(Nc2ccc(cc2)S(N)(=O)=O)c1C#N

InChI Key InChIKey=AHXBLGYPELWYKD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50582924   

TargetCarbonic anhydrase 2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582924(CHEMBL5084107)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582924(CHEMBL5084107)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582924(CHEMBL5084107)
Affinity DataKi:  87nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582924(CHEMBL5084107)
Affinity DataKi:  271nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed