BDBM50583451 CHEMBL5075686

SMILES Cc1ccc(cc1)[C@H]1CC[C@H](N1C(=O)CN[C@@H](CCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=WVLQTFUZRYRSBE-HBMCJLEFSA-N

Data  3 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50583451   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50583451(CHEMBL5075686)
Affinity DataKi:  440nMAssay Description:Inhibition of recombinant human ACE C-domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50583451(CHEMBL5075686)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of recombinant human ACE N-domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50583451(CHEMBL5075686)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of hGH-8His-NEP expressed in CHO cells preincubated for 15 mins followed by MCA-RPPGFDAFK-(Dnp)-OH peptide substrate addition by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed