BDBM50583756 CHEMBL5080497
SMILES Cc1nc2ccc(nc2n1CCCC(F)(F)F)-c1cc(N)nc(N)c1
InChI Key InChIKey=LQSUUCXGVOHOFM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50583756
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of DYRK1A (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of wild type full length DYRK1A (unknown origin) in human U2OS cells assessed as reduction in pSER520 autophosphorylation incubated for 5 ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Human)
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute of Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET as...More data for this Ligand-Target Pair