BDBM50584086 CHEMBL5094947

SMILES O\N=C(/Nc1cccc(Br)c1)c1ccc(CNC(=O)Nc2ccc(cc2)C(F)(F)F)s1

InChI Key InChIKey=KKJUZMCJNOVUQG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584086   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50584086(CHEMBL5094947)
Affinity DataEC50:  293nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50584086(CHEMBL5094947)
Affinity DataIC50:  82nMAssay Description:Inhibition of human IDO1 protein assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate by methylene blue reagent base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed