BDBM50584532 CHEMBL5082328

SMILES [H][C@]12CN([C@@H](CN1C(=O)c1ccncc1[C@]2([H])c1cc2OCOc2c(OC)c1)C(=O)c1ccccc1)C(C)=O

InChI Key InChIKey=QAQIXWAAUHTHBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50584532   

TargetATP-dependent translocase ABCB1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50584532(CHEMBL5082328)
Affinity DataIC50: 940nMAssay Description:Inhibition of P-glycoprotein overexpressed in human SW620/AD300 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed